Using psilocybin to treat drug addiction

There is some evidence that suggests psilocybin may have potential therapeutic effects in helping people with drug addiction. Studies have shown that psilocybin-assisted psychotherapy can help individuals gain a new perspective on their addiction and provide them with insight into the underlying emotional and psychological factors that contribute to their substance abuse.

One study conducted in 2015 by researchers at the University of Alabama at Birmingham found that psilocybin-assisted therapy, combined with cognitive-behavioral therapy, was effective in reducing cocaine use in individuals with a history of cocaine dependence.

Another study conducted in 2019 by researchers at Johns Hopkins University found that psilocybin-assisted therapy was effective in reducing cravings and withdrawal symptoms in individuals with opioid addiction.

In October 2024, Imperial College London announced that Imperial researchers will “explore the potential for psilocybin therapy in drug recovery as part of a landmark trial. The trial, led by Imperial College London, will focus on whether psilocybin – the active compound in magic mushrooms – combined with psychological support, can help to prevent relapse in people who have been addicted to opioids such as heroin.”